PubMed Literatur-Monitor OTC-Wirkstoffe
Aktuelle Reviews und Systematic Reviews mit freiem Volltext zu OTC-Wirkstoffen. Automatisch kuratiert aus der PubMed-Datenbank der National Library of Medicine (NLM/NCBI).
| Datum | Publikation | Wirkstoff |
|---|---|---|
| 26.09. | The Role of Ultra-Low-Dose Naloxone as an Additive in Anesthesia and Nerve Block: A Systematic Review. anesthesia · naloxone · nerve block · systematic review | Lidocain Health Sci Rep (10/2026) |
| 24.09. | Acrodermatitis Dysmetabolica as a Cutaneous Manifestation of Isoleucine Deficiency in Maple Syrup Urine Disease: A Systematic Review of Reported Cases. acrodermatitis · isoleucine · maple syrup urine disease | Zink Health Sci Rep (10/2026) |
| 21.09. | Beyond conventional immunosuppression: tailoring perioperative management protocols for clinical xenotransplantation. CD40 ligand · Cell-free nucleic acids · Disseminated intravascular coagulation · Perioperative care · Xenotransplantation | Heparin Clin Transplant Res (09/2026) |
| 18.09. | The diverse gating mechanisms of bacterial MscS-like ion channels. Ion Channels · Ion Channel Gating · Escherichia coli Proteins · Escherichia coli · Mechanotransduction, Cellular · Bacterial ion channels · Channel gating · Mechanosensitive channels | Escherichia Coli Biochem Soc Trans (09/2026) |
| 17.09. | Microneedle-mediated intelligent combination delivery for hair regeneration: A comprehensive review of technologies, mechanistic evidence, and translational prospects. Androgenetic alopecia · Closed-loop system · Hair regeneration · Intelligent delivery system · Microneedle · Synergistic therapy · Transdermal delivery | Minoxidil Mater Today Bio (10/2026) |
| 11.09. | Metal-Organic Framework-Derived Electrode Materials for Electrochemical Energy Storage: Design Strategies and Applications. MOF‐derived · batteries · energy storage · supercapacitors | Zink ChemSusChem (09/2026) |
| 04.09. | From oxidative stress to epigenetic regulation: Molecular mechanisms of preterm brain injury and neuroprotective strategies (Review). Epigenesis, Genetic · Oxidative Stress · Brain Injuries · Neuroprotective Agents · Infant, Newborn · Infant, Premature · artificial intelligence · biomarkers | Nicotinamid Mol Med Rep (10/2026) |
| 04.09. | Fluoride as a Modifier of Metallome Homeostasis: A Systematic Review of Animal Studies. Dental Caries · Fluorides · Homeostasis · Metals · Trace Elements · animal experimentation · fluorides · metallome | Zink Basic Clin Pharmacol Toxicol (10/2026) |
| 03.09. | Phenome- and laboratory-wide meta-analyses of sickle cell trait reveal multi-system disease associations. Sickle Cell Trait · Phenotype · Phenomics · Genome-Wide Association Study · Kidney Diseases · HBB · LabWAS · PheWAS | Harnstoff Am J Hum Genet (10/2026) |
| 02.09. | Metalloadaptor and metallochaperone proteins reveal new chemical principles of biological metal homeostasis. Homeostasis · Metallochaperones · Metals · Copper · Molecular Chaperones · Zinc | Zink Curr Opin Chem Biol (10/2026) |
| 27.08. | Propionic acidemia as a framework for understanding the impact of disturbed propionyl-CoA on histone modifications. Propionic Acidemia · Histones · Acyl Coenzyme A · Protein Processing, Post-Translational · Propionyl-Coenzyme A Carboxylase · Methylmalonyl-CoA Decarboxylase · Heart · Liver | Methionin Biochem Soc Trans (09/2026) |
| 26.08. | Spinal glial remodeling: a critical driver of inhibitory circuit deterioration and central sensitization in inflammatory pain. Neuroglia · Inflammation · Central Nervous System Sensitization · Pain · Spinal Cord · Neural Inhibition · Astrocytes · Central sensitization | Kaliumchlorid Neurobiol Dis (10/2026) |
| 21.08. | SLC30A8 (ZnT8) at the crossroads of epigenetics and microRNA regulation in type 2 diabetes and nephropathy. Diabetic nephropathy · Epigenetic · MiRNAs · SLC30A8 · Type 2 diabetes · ZnT8 | Zink World J Nephrol (09/2026) |
| 21.08. | The Childhood Cancer and Leukemia International Consortium (CLIC): Expanding global collaboration in pediatric cancer etiology research. Leukemia · Neoplasms · International Cooperation · Registries · Case–control studies · Childhood cancer · Data harmonization · Etiologic research | Folsäure Cancer Epidemiol (10/2026) |
| 20.08. | Metabolic-epigenetic vulnerability in cardiometabolic HFpEF: One-carbon metabolism, DNMT maintenance, and methylation instability. Heart Failure · DNA Methylation · Epigenesis, Genetic · Carbon · Stroke Volume · Cardiometabolic HFpEF · DNA methylation · Epigenetic pharmacology | Nicotinamid Pharmacol Res (10/2026) |
| 19.08. | Zinc-based nanoplatforms for cancer immunotherapy achieved through the cyclic GMP-AMP synthase-stimulator of interferon genes pathway: Bridging tumor metabolism and immune activation. Immunotherapy · Neoplasms · Zinc · cGAS-STING Signaling Pathway · Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase · Nucleotidyltransferases · Signal Transduction · Nanoparticles | Zink Acta Biomater (10/2026) |
| 15.08. | Hypoxia fuels JAK/STAT-LIV1 signaling: A promising therapeutic avenue in triple-negative breast cancer. Triple Negative Breast Neoplasms · Signal Transduction · STAT3 Transcription Factor · Neoplasm Proteins · Janus Kinases · Cation Transport Proteins · Zinc · Epithelial-mesenchymal transition | Zink Biomed Pharmacother (10/2026) |
| 12.08. | The iModulon framework: how x-AI reveals microbial regulatory logic. Bacteria · Transcriptome · Gene Expression Profiling · Computational Biology · Gene Expression Regulation, Bacterial · Artificial Intelligence · AI · systems biology | Escherichia Coli mSystems (09/2026) |
| 11.08. | Oxidative stress and inflammation in neurodegenerative disorders. Oxidative Stress · Neurodegenerative Diseases · Antioxidants · Inflammation · Reactive Oxygen Species · Brain · Antioxidant therapy · Neurodegenerative disorders | Wasserstoffperoxid Arch Toxicol (10/2026) |
| 05.08. | Role of nicotine metabolite ratio in pharmacological interventions on smoking cessation: A systematic review and meta-analyses of randomized controlled trials. Smoking Cessation · Nicotine Replacement Therapy · Nicotine · Randomized Controlled Trials as Topic · Smoking Cessation Agents · Bupropion · Nicotine metabolite ratio · Nicotine replacement therapy | Nicotin Drug Alcohol Depend (10/2026) |
| 05.08. | Co-occurrence of rheumatoid arthritis and calcium pyrophosphate deposition disease: A systematic literature review. Chondrocalcinosis · Arthritis, Rheumatoid · Calcium pyrophosphate deposition disease · Inflammatory polyarthritis · Pseudogout · Rheumatoid arthritis | Prednisolon Semin Arthritis Rheum (10/2026) |
| 05.08. | The Neurological Impact of Metabolic and Bariatric Surgery: A Systematic Review of Post-Operative Neuropathic and Non-Neuropathic Complications. Bariatric Surgery · Postoperative Complications · Nervous System Diseases · Obesity · Peripheral Nervous System Diseases · complications · metabolic and bariatric surgery · neurology | Thiamin (Vitamin B1) Clin Obes (10/2026) |
| 25.07. | Is Capsaicin Effective in Relieving the Symptoms of Burning Mouth Syndrome? A Systematic Review. Capsaicin · Burning Mouth Syndrome · Sensory System Agents · Pain Measurement · Treatment Outcome · Administration, Topical · burning mouth syndrome · capsaicin | Capsaicin J Oral Rehabil (10/2026) |
| 23.07. | Micronutrients and omega-3 PUFAs to promote healthy ageing: informing a physiology-based complementation strategy. Micronutrients · Fatty Acids, Omega-3 · Healthy Aging · Aging · Oxidative Stress · Dietary Supplements · Mitochondria · Immunosenescence | Zink Geroscience (10/2026) |
| 20.07. | The role of metals in cancer and the use of metal chelators as a potential treatment strategy. Neoplasms · Chelating Agents · Antineoplastic Agents · Metals · Apoptosis · Biometals · Cancer · Cancer treatment | Zink Biometals (10/2026) |
| 15.07. | GTP hydrolysis-powered zinc metallochaperones as molecular switches. Hydrolysis · Zinc · Guanosine Triphosphate · Metallochaperones | Zink Curr Opin Chem Biol (10/2026) |
| 14.07. | Compartment-specific Zinc Misallocation in Diabetic Foot Ulcers: Mechanistic Coupling Between Macrophage M1 Locking and MMP-9 Hyperactivation. Matrix Metalloproteinase 9 · Zinc · Diabetic Foot · Macrophages · Diabetic foot ulcer · Macrophage M1 polarization · Matrix metalloproteinase-9 · NF-κB signaling | Zink Biol Trace Elem Res (10/2026) |
| 10.07. | [Medial patellofemoral ligament duplication and lateral lengthening plasty ('soft tissue balancing') according to Urs W. Müller : Partial step in patella stabilization surgery or isolated procedure]. Arthroplasty · Joint Instability · Osteotomy · Patellar Dislocation · Patellar Ligament · Patellofemoral Joint · Plastic Surgery Procedures · Treatment Outcome | Heparin Oper Orthop Traumatol (10/2026) |
| 09.07. | Morbidity and mortality from local anesthetics: localized and systemic toxicity. Anesthetics, Local · Nerve Block · Lidocaine · Risk Factors · Neurotoxicity Syndromes · Anesthesia, Local · local anesthetics · mortality | Lidocain Curr Opin Anaesthesiol (10/2026) |
| 24.06. | Programmed axon degeneration gene variants in human disease. Nicotinamide-Nucleotide Adenylyltransferase · Armadillo Domain Proteins · Cytoskeletal Proteins · Wallerian Degeneration · Axons · Cytokines · Genetic Variation · Axon pathology | Nicotinamid Exp Neurol (10/2026) |
| 23.06. | Sterile abscesses during GnRH agonist therapy for central precocious puberty: a case series and literature review. Abscess · Puberty, Precocious · Gonadotropin-Releasing Hormone · Leuprolide · Puberty Inhibitors · Prognosis · adverse effects · long-acting formulations | Hydrocortison J Pediatr Endocrinol Metab (09/2026) |
| 20.06. | Plant phytohormone electrochemical sensing: From functional materials and interfaces to multiplexed sensor design. Plant Growth Regulators · Electrochemical Techniques · Biosensing Techniques · Indoleacetic Acids · Salicylic Acid · Nanostructures · Abscisic Acid · Flexible electrochemical sensors | Salicylsäure Adv Colloid Interface Sci (10/2026) |
| 17.06. | Arresting root caries with nonrestorative strategies: A systematic review with network meta-analysis. Root Caries · Cariostatic Agents · Sodium Fluoride · Fluoride Treatment · Caseins · Fluorides, Topical · Randomized Controlled Trials as Topic · Silver Compounds | Chlorhexidin J Dent (10/2026) |
| 17.06. | Direct Oral Anticoagulants as Primary or Secondary Treatment for Heparin-Induced Thrombocytopenia (HIT) and Associated Thromboembolism (HITT)-A Meta-Analysis. Thrombocytopenia · Heparin · Administration, Oral · Anticoagulants · Thromboembolism · Treatment Outcome · Hemorrhage · Platelet Count | Heparin Eur J Haematol (10/2026) |
| 17.06. | Management Algorithm for Vasoplegic Shock After Cardiac Surgery: An Interdisciplinary Collaboration. Algorithms · Cardiac Surgical Procedures · Vasoplegia · Shock · Postoperative Complications · Risk Factors · Cardiopulmonary Bypass | Hydroxocobalamin Ann Thorac Surg (10/2026) |
| 17.06. | Functional pituitary adenoma imaging. Pituitary Neoplasms · Adenoma · Positron-Emission Tomography · Magnetic Resonance Imaging · Acromegaly · Cushing’s disease · Pituitary adenoma · Pituitary neuroendocrine tumour | Methionin Rev Endocr Metab Disord (10/2026) |
| 15.06. | Safety and Effectiveness of Direct Oral Anticoagulants Versus Low-Molecular-Weight Heparin for Cancer-Associated Thrombosis: A Systematic Review and Meta-analysis. Administration, Oral · Anticoagulants · Hemorrhage · Heparin, Low-Molecular-Weight · Neoplasms · Randomized Controlled Trials as Topic · Thrombosis · Venous Thromboembolism | Heparin Drug Saf (10/2026) |
| 30.05. | Antiparasitic agents in oncology: Innovative mechanisms, emerging evidence and clinical potential in cancer treatment. Neoplasms · Antineoplastic Agents · Antiparasitic Agents · Anticancer mechanisms · Antiparasitic agents · Cancer stem cells · Drug repurposing · Ivermectin | Niclosamid Eur J Med Chem (10/2026) |
| 16.05. | Preclinical and Emerging Clinical Evidence Supporting the Translational Potential of GLP-1 Receptor Agonists for Treating Psychostimulant and Nicotine Use Disorders. Glucagon-Like Peptide-1 Receptor Agonists · Tobacco Use Disorder · Glucagon-Like Peptide-1 Receptor · Central Nervous System Stimulants · Substance-Related Disorders · Translational Research, Biomedical · Cocaine · GLP-1 | Nicotin Biol Psychiatry (10/2026) |
| 14.05. | Clinical Outcomes of Different Heparin Anticoagulation Monitoring Targets in Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-analysis. Extracorporeal Membrane Oxygenation · Heparin · Anticoagulants · Treatment Outcome · Partial Thromboplastin Time · Blood Coagulation · Hemorrhage · Thrombosis | Heparin J Cardiothorac Vasc Anesth (10/2026) |
| 02.05. | Rapidly progressive pediatric fibronectin glomerulopathy driven by a novel FN1 mutation (p.Thr1917del): implications for early diagnosis and recognition of systemic involvement. Fibronectins · Glomerulonephritis, Membranoproliferative · Early Diagnosis · Kidney · Disease Progression · Retrospective Studies · Biopsy · Genetic Association Studies | Heparin Pediatr Nephrol (10/2026) |
| 29.04. | Update in childhood asthma. Asthma · Phenotype · Anti-Asthmatic Agents · Child, Preschool · Disease Management · Adrenal Cortex Hormones · Asthma attack · Eosinophil | Prednisolon Allergol Int (10/2026) |
| 12.04. | Therapeutic Potential of Glucagon-Like Peptide-1 Receptor Agonists for Smoking Cessation. Glucagon-Like Peptide-1 Receptor Agonists · Smoking Cessation · Smoking Cessation Agents · Addiction · Glucagon-like peptide-1 · Nicotine · Semaglutide · Smoking cessation | Nicotin Biol Psychiatry (10/2026) |
| 11.03. | Can trigeminal sensations impact saltiness perception? A mini-review. Taste · Taste Perception · Trigeminal Nerve · Sodium Chloride · cross‐modal interaction · saltiness · sensory evaluation · sodium reduction | Capsaicin J Sci Food Agric (10/2026) |
| 27.02. | Intravenous Lidocaine in Video-Assisted Thoracoscopic Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Lidocaine · Thoracic Surgery, Video-Assisted · Randomized Controlled Trials as Topic · Anesthetics, Local · Postoperative Pain · Postoperative Nausea and Vomiting · VATS · analgesia | Lidocain J Cardiothorac Vasc Anesth (10/2026) |
| 16.02. | Epidemiology, Diagnosis and Management of Alopecia Areata: An Asia-Pacific Modified Delphi Expert Panel Recommendations. Adrenal Cortex Hormones · Alopecia Areata · Asia · Biopsy · Delphi Technique · Dermoscopy · Injections, Intralesional · Janus Kinase Inhibitors | Minoxidil Int J Dermatol (10/2026) |
| 07.01. | The Role of Immunological Challenges, Oxidative Stress, and Dietary Interventions in Managing Hashimoto's Thyroiditis: A Narrative Review. Oxidative Stress · Hashimoto Disease · Thyroid Gland · Diet · Reactive Oxygen Species · Hashimoto thyroiditis · autoimmunization · clinical nutrition | Zink Nutr Rev (10/2026) |
| 19.11. | Optimizing Autologous Fat Grafting: A Systematic Review of Enhancement Strategies and Graft Survival. Graft Survival · Adipose Tissue · Transplantation, Autologous · Mammaplasty · Stromal Vascular Fraction · Autografts · Platelet-Rich Plasma | Acetylcystein Aesthet Surg J (10/2026) |
| 17.10. | Deep and disseminated dermatophytosis in immunocompromised populations-A systematic review. Antifungal Agents · Dermatomycoses · Immunocompromised Host · Risk Factors · Tinea · deep dermatophytosis · dermatophyte · disseminated fungal infection | Terbinafin J Eur Acad Dermatol Venereol (10/2026) |
| 24.09. | N-acetylcysteine for Parkinson's disease: a translational systematic review of mechanistic and early clinical data. Acetylcysteine · Antioxidants · Neuroprotective Agents · Oxidative Stress · Parkinson Disease · N-acetylcysteine · Parkinson’s disease · glutathione | Acetylcystein Neurodegener Dis Manag (10/2026) |
| - | Elevated methionine in plants: the effect on development, stress responses, epigenetics, and nutritional biofortification. | Methionin J Exp Bot (09/2026) |
| - | Sulfur in dialogue with phosphorus, nitrogen, and iron: regulatory networks in plant nutrient homeostasis. | Methionin J Exp Bot (09/2026) |
| - | Birth outcomes following intrauterine exposure to electronic nicotine delivery systems: a systematic review and meta-analysis. | Nicotin Nicotine Tob Res (09/2026) |
| - | Precision bacteriophage therapy for multidrug-resistant recurrent urinary tract infections: From biological rationale to clinical translation in Taiwan. | Escherichia Coli Tzu Chi Med J |
| - | Escherichia coli with penicillin-binding protein 3 insertions: implications for newer β-lactam/β-lactamase inhibitor combinations. | Escherichia Coli Antimicrob Agents Chemother (10/2026) |
| - | Relationship Between Hypovitaminosis C, Obesity, and Features of Metabolic Syndrome-A Narrative Review. | Ascorbinsäure Nutr Rev (10/2026) |
| - | Early Analgesia for the Management of Acute Pancreatitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. | Paracetamol Pancreas (10/2026) |
| - | Historical contributions and future horizons of Japanese orthopaedic oncology: from surgical innovation to nationwide collaborations. | Coffein Int Orthop (10/2026) |
| - | Impact of nutritional factors on the pharmacokinetics of antipsychotics - a systematic review. | Coffein Psychiatry Res (10/2026) |
| - | A Pathophysiological Approach for Early Detection and Prevention of AKI in the NICU. | Coffein Am J Perinatol (10/2026) |
| - | Imipenem resistance in Escherichia coli isolates from ICU patients: A systematic review and meta-analysis. | Escherichia Coli New Microbes New Infect (10/2026) |
| - | Antivirulence strategies targeting adhesion and biofilm formation in uropathogenic E. coli: Recent advances and clinical perspectives-review. | Escherichia Coli Microb Pathog (10/2026) |
| - | Role of pks + Escherichia coli in colorectal cancer: Mechanisms, clinical evidence, and therapeutic perspective. | Escherichia Coli Infect Genet Evol (10/2026) |
| - | Bacterial Laccase: Recent Advances in Production, Engineering Strategies, and Diagnostic Applications. | Escherichia Coli Biotechnol Bioeng (10/2026) |
| - | Microbiome-Derived Tryptophan Metabolites Regulate AhR Signaling to Restore Epithelial Barrier Integrity in Inflammatory Bowel Disease. | Lactobacillus Microbiologyopen (10/2026) |
| - | Beyond Acidification: Microbial Lactate in the Oral Microbiome-Host Axis. | Lactobacillus J Dent Res (10/2026) |
| - | Probiotic, prebiotic, and synbiotic interventions targeting the early-life gut-brain axis: A systematic review of randomized controlled trials. | Lactobacillus J Neuroimmunol (10/2026) |
| - | Patch Testing in Paediatric Drug Hypersensitivity Reactions: Current Evidence and Clinical Implications. | Paracetamol Contact Dermatitis (10/2026) |
| - | Arginase 1 Deficiency. | Harnstoff (1993) |
| - | Ataxia-Telangiectasia. | Nicotinamid (1993) |
| - | Cystic Fibrosis. | Harnstoff (1993) |